Lab News
Our manuscript “Animal Model Considerations for Chordoma Research: Reproducing the Tumor Microenvironment In Vivo with Humanized Mice” was published in Frontiers in Oncology, section Cancer Immunity and Immunotherapy!
Campilan B, Schroeder C, Sagaityte E, Arditi J, Leary OP, Gokaslan ZL, Sullivan PLZ and Martinez-Moreno M (2024) Animal model considerations for chordoma research: reproducing the tumor microenvironment in vivo with humanized mice. Front. Oncol. 14:1330254. doi: 10.3389/fonc.2024.1330254
Congratulations to Kaylee Gallagher and Christian Godinez for their wonderful poster presentation and flash talk, which received an award at the Legorreta Cancer Center 2024 Cancer Biology Program Retreat!
Congratulations to both Victoria Chamberlain and Tati-Anna Robinson for receiving a BrownConnect SPRINT|UTRA for the upcoming spring semester!
Alexis Andrade joined the lab as a master’s student
Madison Michles joined the lab as a medical student
At the beginning of the Fall 2023 semester, we welcomed several new students! Jessica Ding, Victoria Chamberlain, Tati-Anna Robinson, Benjamín Córdova Herrera, and Zill Patel joined as undergraduate research assistants, Tyler Owens as a medical student, and Temitope Aina as our first master’s student
Our first paper as the Chordoma Center was accepted and published online!
Margot Martinez Moreno, Elaina Wang, Christian Schroeder, Patricia Sullivan & Ziya Gokaslan (2023) Shedding light on emerging therapeutic targets for chordoma, Expert Opinion on Therapeutic Targets, 27:8, 705-713, DOI: 10.1080/14728222.2023.2248382
Christian Godinez joined the lab as an undergraduate research assistant
Jonathan Arditi joined the lab as a medical student
With generous support from the Rhode Island Foundation, we were awarded a Medical Research Grant for the research project entitled “The epigenetic regulatory network of brachyury in chordoma” (submitted by Dr. Martinez-Moreno). Starting in June, this pilot project will study the differential binding of brachyury, a transcription factor, to different motifs via ChIP-seq experiments and analysis. If successful, this pilot project will be the foundation to uncover the epigenetic regulatory networks of brachyury in chordoma oncogenesis and progression.
Bea Campilan joined the lab as our first research assistant
From September 2022 to March 2023, we have set up our lab spaces, including the 2 independent laboratories, a BL2 cell culture room and a dedicated BL2 animal suite, that includes a dedicated surgery room and a state-of-the-art biohazard racks to house NuJ mice.
Dr. Patricia Sullivan, MD, has been appointed Assistant Professor of Neurosurgery and Director of the Center of Spine Tumor and Chordoma Research. Dr. Margot Martinez-Moreno, PhD, has been appointed Assistant Professor of Neurosurgery, and Director of the Spinal Tumor Epigenetics Laboratory/Co-Director of the CSTCR.