Selected Publications:
Sinclair AN, Huynh CT, Sladewski TE, Zuromski JL, Ruiz AE, de Graffenried CL. The Trypanosoma brucei subpellicular array is organized into functionally discrete subdomains defined by microtubule associated proteins. Uploaded to BioRXiv & under review.
Campbell, PC & de Graffenried CL. Alternate histories of cytokinesis: lessons from the trypanosomatids. Molecular Biology of the Cell, in press.
Sinclair, AN & de Graffenried CL. More than Microtubules: The Structure and Function of the Subpellicular Array in Trypanosomatids. Trends in Parasitology, 2019.
Hilton NA, Sladewski TE, Perry JA, Pataki Z, Sinclair-Davis AN, Muniz RS, et al. Identification of TOEFAZ1-interacting proteins reveals key regulators of Trypanosoma brucei cytokinesis. Molecular Microbiology; 2018.
Perry JA, Sinclair-Davis AN, McAllaster MR, de Graffenried CL. TbSmee1 regulates hook complex morphology and the rate of flagellar pocket uptake in Trypanosoma brucei. Molecular Microbiology; 2018.
Sinclair-Davis AN, McAllaster MR, de Graffenried CL. A functional analysis of TOEFAZ1 uncovers protein domains essential for cytokinesis in Trypanosoma brucei. Journal of Cell Science; 2017.
McAllaster MR, Sinclair-Davis AN, Hilton NA, de Graffenried CL. A unified approach towards Trypanosoma brucei functional genomics using Gibson assembly. Molecular and Biochemical Parasitology; 2016.
McAllaster MR, Ikeda KN, Lozano-Núñez A, Anrather D, Unterwurzacher V, Gossenreiter T, et al. Proteomic identification of novel cytoskeletal proteins associated with TbPLK, an essential regulator of cell morphogenesis in Trypanosoma brucei. Molecular Biology of the Cell; 2015.
de Graffenried CL, Anrather D, Raußendorf Von F, Warren G. Polo-like kinase phosphorylation of bilobe-resident TbCentrin2 facilitates flagellar inheritance in Trypanosoma brucei. Molecular Biology of the Cell; 2013.
Lozano-Nunez A, Ikeda KN, Sauer T, de Graffenried CL. An analogue-sensitive approach identifies basal body rotation and flagellum attachment zone elongation as key functions of PLK in Trypanosoma brucei. Molecular Biology of the Cell; 2013.
Ikeda KN, de Graffenried CL. Polo-like kinase is necessary for flagellum inheritance in Trypanosoma brucei. Journal of Cell Science; 2012.
de Graffenried CL, Ho HH, Warren G. Polo-like kinase is required for Golgi and bilobe biogenesis in Trypanosoma brucei. Journal of Cell Biology; 2008.