News

PhD Defense: 3D neural microtissues as a platform to study neuropathology of mechanical injury and glioblastoma

April 15, 2025

Congratulations to Dr. Dom Calvao on a successful PhD defense! In April 2025, Dom successfully defended his PhD thesis based on his research in the Hoffman-Kim Lab. He delivered an outstanding presentation at Brown University, sharing his work on glioblastoma and traumatic brain injury. We are incredibly proud of his accomplishments and excited to see what he does next!

Development and optimization of a device for simulating traumatic brain injury impacts using an in vitro 3D cortical spheroid model

New England Science Symposium, March 2025

Francesca recently presented her poster on “Development and optimization of a device for simulating traumatic brain injury impacts using an in vitro 3D cortical spheroid model” at the New England Science Symposium in Boston in March 2025.

A 3D multi-cellular cortical microtissue model for the study of glioblastoma multiforme pathology and therapeutic screening

Keystone Symposium on the Neural Influence of Cancer, January 2025

Dom gave both an oral and poster presentation at the 2025 Keystone Symposium on the Neural Influence on Cancer, Tumor Microenvironment and Cancer Immunology entitled A 3D multi-cellular cortical microtissue model for the study of glioblastoma multiforme pathology and therapeutic screening.

Cortical Microtissues: A 3d In Vitro Neuroimmune Model To Probe Microglia Dynamics Across Development and Neuroinflammation

American Society for Cell Biology, December 2024

Alex recently presented his work on neuroinflammation at the American Society for Cell Biology (ASCB) Conference in 2024. This work is entitled Cortical Microtissues: A 3d In Vitro Neuroimmune Model To Probe Microglia Dynamics Across Development and Neuroinflammation.

Characterization of Ischemia with Reperfusion in a Three-Dimensional Cortical Spheroids Model.

Society for Neuroscience, November 2023

Ilayda recently attended the Society for Neuroscience Conference in Washington, D.C. in November 2023. She presented her poster titled “Characterization of Ischemia with Reperfusion in a Three-Dimensional Cortical Spheroids Model.” The ischemia model of the lab has been recently published, titled “Cortical Spheroid Model for Studying the Effects of Ischemic Brain Injury.” doi: 10.1007/s44164-023-00046-z. The publication was also featured on the Carney Institute for Brain Science website: https://graduateschool.brown.edu/news/2023-07-12/stroke-therapy-screening.