Publications

Human Neurons from Christianson Syndrome IPSCs Reveal Mutation-Specific Responses to Rescue Strategies. Lizarraga S, Li M, Maguire A, van Dyck L, Wu Q, Ouyang Q, Kavanaugh B, Hoffman-Kim D., et al. 2021. Science Translational Medicine 13 (580). https://doi.org/10.1126/scitranslmed.aaw0682.

Schwann cell durotaxis can be guided by physiologically relevant stiffness gradients. Evans EB, Brady SW, Tripathi A, Hoffman-Kim D. Biomater Res. 2018 May 9;22:14. doi: 10.1186/s40824-018-0124-z. eCollection 2018.

A three-dimensional neural spheroid model for capillary-like network formation. Boutin ME, Kramer LL, Livi LL, Brown T, Moore C, Hoffman-Kim D. J Neurosci Methods. 2018 Apr 1;299:55-63. doi: 10.1016/j.jneumeth.2017.01.014. Epub 2017 Jan 29.

Protein characterization of intracellular target-sorted, formalin-fixed cell subpopulations. Sadick JS, Boutin ME, Hoffman-Kim D, Darling EM. Sci Rep. 2016 Sep 26;6:33999. doi: 10.1038/srep33999.

A biomimetic synthetic feeder layer supports the proliferation and self-renewal of mouse embryonic stem cells. López-Fagundo C, Livi LL, Ramchal T, Darling EM, Hoffman-Kim D. Acta Biomater. 2016 Jul 15;39:55-64. doi: 10.1016/j.actbio.2016.04.047. Epub 2016 Apr 30.

Three-Dimensional Neural Spheroid Culture: An In Vitro Model for Cortical Studies. Dingle YT, Boutin ME, Chirila AM, Livi LL, Labriola NR, Jakubek LM, Morgan JR, Darling EM, Kauer JA, Hoffman-Kim D. Tissue Eng Part C Methods. 2015 Dec;21(12):1274-83. doi: 10.1089/ten.TEC.2015.0135. Epub 2015 Oct 6.

Application and assessment of optical clearing methods for imaging of tissue-engineered neural stem cell spheres. Boutin ME, Hoffman-Kim D. Tissue Eng Part C Methods. 2015 Mar;21(3):292-302. doi: 10.1089/ten.TEC.2014.0296. Epub 2014 Sep 19.

Three-dimensional traction forces of Schwann cells on compliant substrates. López-Fagundo C, Bar-Kochba E, Livi LL, Hoffman-Kim D, Franck C. J R Soc Interface. 2014 Aug 6;11(97):20140247. doi: 10.1098/rsif.2014.0247.

High resolution, large deformation 3D traction force microscopy. Toyjanova J, Bar-Kochba E, López-Fagundo C, Reichner J, Hoffman-Kim D, Franck C. PLoS One. 2014 Apr 16;9(4):e90976. doi: 10.1371/journal.pone.0090976. eCollection 2014.

Navigating neurites utilize cellular topography of Schwann cell somas and processes for optimal guidance. López-Fagundo C, Mitchel JA, Ramchal TD, Dingle YT, Hoffman-Kim D. Acta Biomater. 2013 Jul;9(7):7158-68. doi: 10.1016/j.actbio.2013.03.032. Epub 2013 Apr 1.

Neurient: an algorithm for automatic tracing of confluent neuronal images to determine alignment. Mitchel JA, Martin IS, Hoffman-Kim D. J Neurosci Methods. 2013 Apr 15;214(2):210-22. doi: 10.1016/j.jneumeth.2013.01.023. Epub 2013 Feb 4.

WITHDRAWN: Corrigendum to “A novel method for analyzing images of live nerve cells” [J. Neurosci. Methods 201 (2011) 98-105]. Kim KM, Kim SY, Minxha J, Richardson J, Hoffman-Kim D, Palmore GT. J Neurosci Methods. 2012 Jul 17. pii: S0165-0270(12)00255-5. doi: 10.1016/j.jneumeth.2012.07.001. [Epub ahead of print]

Cellular scale anisotropic topography guides Schwann cell motility. Mitchel JA, Hoffman-Kim D. PLoS One. 2011;6(9):e24316. doi: 10.1371/journal.pone.0024316. Epub 2011 Sep 20.

Quantitative control of neuron adhesion at a neural interface using a conducting polymer composite with low electrical impedance. Kim SY, Kim KM, Hoffman-Kim D, Song HK, Palmore GT. ACS Appl Mater Interfaces. 2011 Jan;3(1):16-21. doi: 10.1021/am1008369. Epub 2010 Dec 13.

The importance of defining ‘data’ in data management policies: Commentary on: “Issues in data management”. Richardson J, Hoffman-Kim D. Sci Eng Ethics. 2010 Dec;16(4):749-51. doi: 10.1007/s11948-010-9231-5. Epub 2010 Sep 19.

Optimization by Response Surface Methodology of Confluent and Aligned Cellular Monolayers for Nerve Guidance. Kofron CM, Hoffman-Kim D. Cell Mol Bioeng. 2009 Dec;2(4):554-572.

Neurite outgrowth at the biomimetic interface. Kofron CM, Liu YT, López-Fagundo CY, Mitchel JA, Hoffman-Kim D. Ann Biomed Eng. 2010 Jun;38(6):2210-25. doi: 10.1007/s10439-010-0054-y. Epub 2010 May 4.

Topography, cell response, and nerve regeneration. Hoffman-Kim D, Mitchel JA, Bellamkonda RV. Annu Rev Biomed Eng. 2010 Aug 15;12:203-31. doi: 10.1146/annurev-bioeng-070909-105351. Review.

Neurite outgrowth at the interface of 2D and 3D growth environments. Kofron CM, Fong VJ, Hoffman-Kim D. J Neural Eng. 2009 Feb;6(1):016002. doi: 10.1088/1741-2560/6/1/016002. Epub 2008 Dec 22.

Evaluation of neurite outgrowth anisotropy using a novel application of circular analysis. Li GN, Hoffman-Kim D. J Neurosci Methods. 2008 Sep 30;174(2):202-14. doi: 10.1016/j.jneumeth.2008.07.001. Epub 2008 Jul 11.

Dynactin is essential for growth cone advance. Abe TK, Honda T, Takei K, Mikoshiba K, Hoffman-Kim D, Jay DG, Kuwano R. Biochem Biophys Res Commun. 2008 Aug 1;372(3):418-22. doi: 10.1016/j.bbrc.2008.05.008. Epub 2008 May 12.

Tissue-engineered platforms of axon guidance. Li GN, Hoffman-Kim D. Tissue Eng Part B Rev. 2008 Mar;14(1):33-51. doi: 10.1089/teb.2007.0181. Review.

Multi-molecular gradients of permissive and inhibitory cues direct neurite outgrowth. Li GN, Liu J, Hoffman-Kim D. Ann Biomed Eng. 2008 Jun;36(6):889-904. doi: 10.1007/s10439-008-9486-z. Epub 2008 Apr 5.

Biomimetic materials replicating Schwann cell topography enhance neuronal adhesion and neurite alignment in vitro. Bruder JM, Lee AP, Hoffman-Kim D. J Biomater Sci Polym Ed. 2007;18(8):967-82.

Chromophore-assisted laser inactivation. Hoffman-Kim D, Diefenbach TJ, Eustace BK, Jay DG. Methods Cell Biol. 2007;82:335-54.

Genomic and morphological changes of neuroblastoma cells in response to three-dimensional matrices. Li GN, Livi LL, Gourd CM, Deweerd ES, Hoffman-Kim D. Tissue Eng. 2007 May;13(5):1035-47.

Fabrication of polymeric replicas of cell surfaces with nanoscale resolution. Bruder JM, Monu NC, Harrison MW, Hoffman-Kim D. Langmuir. 2006 Sep 26;22(20):8266-70.

Neurite bridging across micropatterned grooves. Goldner JS, Bruder JM, Li G, Gazzola D, Hoffman-Kim D. Biomaterials. 2006 Jan;27(3):460-72. Epub 2005 Aug 22.

Comparison of three myofibroblast cell sources for the tissue engineering of cardiac valves. Hoffman-Kim D, Maish MS, Krueger PM, Lukoff H, Bert A, Hong T, Hopkins RA. Tissue Eng. 2005 Jan-Feb;11(1-2):288-301.

Tricuspid valve biopsy: a potential source of cardiac myofibroblast cells for tissue-engineered cardiac valves. Maish MS, Hoffman-Kim D, Krueger PM, Souza JM, Harper JJ 3rd, Hopkins RA. J Heart Valve Dis. 2003 Mar;12(2):264-9.

pp60(c-src) is a negative regulator of laminin-1-mediated neurite outgrowth in chick sensory neurons. Hoffman-Kim D, Kerner JA, Chen A, Xu A, Wang TF, Jay DG. Mol Cell Neurosci. 2002 Sep;21(1):81-93.