Past and current studies focus on: the characterization of bacterial adherence on spinal implants of various compositions, preventative measures independent of antibiotics, in the form of biocompatible antimicrobial silver-doped Titanium Dioxide: Polydimethylsiloxane antimicrobial coating. Translation of antimicrobial coating on prosthetic liners, spinal implants, and catheters. Additionally, through the development of a Confocal Laser Scanning Microscopy and fluorescent conjugated antibodies, our team has developed an assay capable of directly visualizing and quantifying bacterial and fungal colonization and biofilm formation directly on explants, tissue, and synovial fluid before the patient leaves the operating room.
The Diane N. Weiss Center for Orthopaedic Trauma Research’s translational approach towards tackling the challenges of modern day bacterial infections are grounded in a philosophy of diversity, respect, and acceptance. Our research team is led by Co-Directors Christopher Born, MD and Dioscaris Garcia, PhD. Our team is made up of a tapestry of graduate, medical, and undergraduate students united by the common base of mutual respect, equity of diversity, and productivity.