The drug overdose crisis has had dramatic effects on people who use drugs. Peer overdose response workers (peer responders), i.e., people with lived/living experience of drug use who work in overdose response settings, are especially at risk of the negative physical and mental health effects of the crisis—that is, doing this work can take a toll on their bodies and minds. However, scientists have not studied or measured the effect of peer overdose response work on the people doing this work (peer responders).