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NEWS

 

  • (November 2022) Aaliyah Battle presented her work in the Holder Lab at the 2022 ABRCMS conference in Anaheim, CA in the Cancer Biology poster symposium. Special congratulations for presenting at her first national meeting! Aaliyah was also awarded a Research at Brown (RAB) grant to support her travels to ABRCMS!

 

  • (November 2022) Elias Eteshola, PhD presented his work in the Holder lab “The influence of PIM1 Kinase on Survival in Renal Cell Carcinoma” at the Warren Alpert Medical School Academic Symposium and was awarded Best Presentation in the Clinical Medicine Category! Congratulations Elias!

 

  • (October 2022) Kimberly Meza presented her thesis work at the 2022 SACNAS NDiSTEM conference in San Juan, PR in the Cancer Biology Graduate Student Oral Presentations session.  Congratulations Kim!

 

  • (October 2022) Sheldon L. Holder, MD, PhD received an award from Cures Within Reach to fund a clinical trial, “Repurposing degarelix to treat androgen receptor positive bladder cancer.”  See the 7-minute pitch video and learn more here.

 

  • (October 2022) Aaliyah Battle’s abstract titled “Investigating an IL-6/JAK-independent axis that modulates PIM1 protein expression in RCC” was accepted for a poster presentation at the Annual Biomedical Research Conference for Minoritized Scientists (ABRCMS) 2022 scheduled for November 2022. She also was awarded a travel award!

 

  • (September 2022) Kimberly Meza was awarded a National Institutes of Health National Cancer Institute Diversity Supplement on co-mentor Dr. Wafik El-Deiry’s R01 titled  “ONC201/TIC10 Anti-tumor Effect Through Regulation of the TRAIL pathway”  to support her research in understanding the contribution of PIM kinases to TRAIL mediated apoptosis in RCC.

 

  • (September 2022) Sheldon L. Holder, MD PhD was awarded a Brown Physicians Incorporated Academic Assessment Award in a collaborative project with Dr. Thomas Ollila and Dr. Patrycja Dubielecka-Szczerba to study “PIM Inhibition in Defined Genetic Subtypes of Diffuse Large B-Cell Lymphoma.”

 

  • (September 2022) Sheldon L. Holder, MD, PhD was awarded a Kidney Cancer Association Trailblazer Award for the “Exploration of the Causes and Effects of Increased PIM1 Kinase Activity in Renal Cell Carcinoma.“

 

  • (August 2022) Aaliyah Battle and Braden Donoian were awarded Brown University SPRINT|UTRA awards for Fall 2022 to conduct research in the Holder Lab. Aaliyah will continue her  investigations of PIM1 mechanisms in RCC and Braden will start a project looking at the role of circulating tumor cells from RCC patient blood samples.

 

  • (August 2022) Aaliyah Battle and Paige Eversole presented their summer research projects at the Brown Summer Research Symposium poster session. Aaliyah presented her work titled “Detection of a JAK independent pathway to PIM1 overexpression in RCC” and Paige presented her work titled “The Effect of Androgen Signaling on Cisplatin/Gemcitabine Chemotherapy Resistance in Bladder Cancer”. 

 

  • (June 2022) Kimberly Meza successfully passed her qualifying exam, Oncogenic Mechanisms in Renal Cell Carcinoma: PIM1 and DR5 Expression.  Congratulations Kim, PhD Candidate!

 

  • (June 2022) The Holder lab welcomes Leadership Alliance SR-EIP rising senior undergraduate student Paige Eversole for the summer. Paige will be investigating the role of androgen receptor signaling in bladder cancer. Welcome Paige!

 

  • (May 2022) Kimberly Meza’s abstract titled “Characterizing an IL-6 induced PIM1 Expression Pathway in Renal Cell Carcinoma” was accepted for oral presentation at the 2022 Society for Advancement of Chicanos/Hispanics and Native Americans in Science meeting scheduled for October 2022. Kim was also awarded a travel award!

 

  • (March 2022) Aaliyah Battle was awarded a Brown University SPRINT|UTRA award to spend the summer in the Holder Lab to investigate mechanisms of PIM1 expression in RCC.

 

  • (February 2022) Kimberly Meza presented a poster titled “Targeting an IL_6/JAK/STAT/PIM1 pathway in renal cell carcinoma” at the American Society for Clinical Oncology (ASCO) Genitourinary Cancers Symposium in San Francisco, CA.

 

  • (August 25, 2021) Sheldon L. Holder, MD, PhD was invited to join the inaugural cohort of the National Medical Fellowships and Bristol Myers Squibb Foundation Diversity in Clinical Trials Career Development Program.  This is a two-year award for Dr. Holder’s project to increase diversity in clinical trial participants in the GU Oncology program at the Cancer Center at Brown University and Lifespan Cancer Institute.

 

  • (July 30, 2021) The Holder Lab was mentioned in the business section of the Boston Globe in an article detailing Brown University’s on-going pursuit to grow the Cancer Center at Brown University into an NCI-designated cancer center.  Click here to read the article.