The Cardiac and Vascular Biology Research Programs at VA Providence Healthcare Center and Brown University Health Cardiovascular Institute include robust, preclinical, clinical, and outcome-based research.

Our commitment to excellence in cardiac and vascular biology research drives innovative advancements in cardiovascular health. Our multidisciplinary team of researchers and clinicians collaborates across several specialized centers to translate groundbreaking discoveries from bench to bedside.

Our Programs

A collaborative environment dedicated to groundbreaking research in vascular biology and cardiovascular health.

Vascular Research Laboratory (VRL)

Located at the VA Providence Healthcare System, the VRL brings together clinical, translational and health services science experts dedicated to understanding cardiac and vascular diseases. Our collaborative efforts strive to develop innovative treatments for conditions such as pulmonary hypertension, heart failure, atherosclerosis, peripheral vascular disease and lung diseases.

MEET THE INVESTIGATORS →

Cardiovascular Research Center (CVRC)

At the Brown University Health CVRC, we delve into the fundamental mechanisms underlying cardiovascular diseases. The state-of-the-art facilities at CVRC enable in-depth studies on genetically modified models, focusing on areas such as molecular mechanisms of cardiac arrhythmias, sudden cardiac death, cardiomyocyte hypertrophy, heart failure, atherosclerosis and lipid disorders.

MEET THE INVESTIGATORS →

Research by the Numbers

$8.09M

FUNDED TO THE BROWN DIVISION OF CARDIOLOGY

$3.19M

FUNDED TO THE BUH & CVI

$4.90M

FUNDED TO THE VA & VRL

200+

TOTAL PUBLICATIONS

49

CLINICAL TRIALS

31

TOTAL PRINCIPAL INVESTIGATORS

10

ACTIVE CLINICAL INVESTIGATORS

12

NIH R01 Grants

4

VA MERIT Review Awards

2

NIH R21 Grants

2

American Heart Association (AHA) Grants

1

VA Career Development Award (CDA)

1

NIH P20 Center Grant

1

NIH P30 Core Center Grant

1

R44 Small Business Innovation Research (SBIR) Grant

1

Department of Defense (DOD) Grant

Pilot & Foundation Awards

COBRE Research Project Leader

Collaborative Research and Clinical Trials

Partnering across specialized centers to transform groundbreaking discoveries into clinical solutions.

Cardiopulmonary Vascular Biology Center of Biomedical Research Excellence (CPVB COBRE)

Supported by a significant NIH grant, the CPVB COBRE focuses on elucidating the pathogenesis and treatment of vascular pathobiology in lung and heart diseases. By fostering a multidisciplinary approach, the center supports pilot projects and provides state-of-the-art core services to translate our research findings into effective therapies for blood vessel diseases.

LEARN MORE →

Clinical Trials Program

Our Clinical Trials Program at Brown University Health and at VA Providence supports high-quality clinical and translational research in cardiovascular diseases. Through partnerships with VISN1 Clinical Trials Network at the VA and Brown University Health’s Office of Research Administration, we provide services that facilitate the seamless translation of research discoveries into clinical applications, offering eligible patients access to cutting-edge treatments.

LEARN MORE →