TREATMENT STUDIES
LINC: Liaison Intervention for Navigating Care: A Treatment Engagement Study for Psychiatrically Hospitalized Adolescents at Clinical High Risk for Psychosis (PI: Thompson; Mentors: Spirito and Guadiano).
This study is exploring the development and feasibility of a brief family-oriented intervention for hospitalized adolescents with psychosis-spectrum symptoms, to promote treatment engagement and service use after discharge.
OWL -Online Wise Learning: Computer-Assisted Parenting Intervention in Community Mental Health Settings (PI: Wolff; Mentor: Spirito).
Dr. Wolff and her research team are conducting a study regarding ways to engage parents in DBD adolescent treatment. This includes testing a computerized parenting intervention, Parenting Wisely (PW). Computerized treatment such as this broadens availability and works toward meeting needs of families in a more timely and efficient manner. This program could provide needed structure to parent involvement, thus relieving pressure on clinicians to do so alone.
Evidence-Based Parent Group Treatment for Children with Mood Disorders (PI: MacPherson).
This study will adapt an evidence-based treatment for pediatric mood disorders, Psychoeducational Psychotherapy, to a parent-only group to enhance fit in a clinical practice setting, and evaluate preliminary implementation, effectiveness, and multi-level treatment mechanisms.
Lamotrigine as a Candidate Pharmacotherapy for Adolescent (PI: Miranda).
This clinical trial will evaluate the feasibility, acceptability, tolerability and initial efficacy of lamotrigine for treating alcohol use disorder in adolescents.
Enhancing the Effects of Adolescent Alcohol Treatment with Atomexetine (PI: Miranda).
This proof-of-concept clinical trial leverages human laboratory paradigms and ecological momentary assessment (EMA) methods to test the effects of atomoxetine on alcohol use among adolescents with alcohol use disorder.
Online Peer Experiences and Suicidal Behavior (PI: Nesi, Mentors: Spirito, Wolff).
This mixed-method study uses qualitative interviews and social media data to explore the role of online peer experiences as risk and protective factors for suicidal behavior in high-risk adolescents.
ASSESSMENT STUDIES
Parenting and Social Media Use (PI: Nesi, Mentor: Wolff).
This study aims to understand the effectiveness of parenting strategies in managing teens’ social media use, using ecological momentary assessment (EMA), questionnaires, and observations of parent-child interactions.
Patient Perspectives of Adolescent Inpatient Psychiatric Hospitalization and Transition to Home. (PI: Dr. Wolff)
The purpose of this study is to understand how inpatient hospitalization affects treatment outcomes for teens with mental health concerns after discharge and to learn more about patients’ transition home after discharge. The study is recruiting teens 12-17 years old from the Bradley Hospital AIU. Parents are also invited to participate, though the parent can decline with no effect on their child’s enrollment in the study. The study consists of completing surveys while inpatient or shortly after discharge and 1-month post-discharge, daily phone surveys for teens, and a qualitative interview for parents.
Social Media Utilization and Sleep Pilot (PI: Dr Kudinova)
This study focuses on teens’ use of social media and its implications for mental health symptoms and sleep regulation. The study recruits teens 15-18 years old from Bradley Hospital AIU and Partial programs. The participants must have a history of SI, attempts, or SIB and a guardian that can also participate. The study takes place over two sessions that can be virtual or in person. The first session involves self reports surveys. The second is an at-home spit night where participants collect saliva samples over a period of 5 hours with guidance from researchers. There is also a three week period between study sessions where participants will wear an actigraphy watch that monitors sleep. During this time they will receive multiple daily surveys through a phone app and email that address mental health symptoms and sleep.
The Longitudinal and Proximal Roles of Rejection and Rejection Sensitivity in Suicidality and Non-suicidal Self-injury among Sexual Minority Adolescents (PI: Poon, Mentor: Spirito).
This study is using Ecological Momentary Assessment and other methods to identify longitudinal and proximal risk factors for suicidal thoughts and behaviors (STBs) and non-suicidal self-injury (NSSI) among psychiatrically-hospitalized adolescents up to 18 mos post-discharge—particularly those who identify as sexual minorities (e.g., gay, lesbian, bi+).
Safety Net: A Qualitative Study of Psychosis and Suicidality to Inform Safety Planning for High-Risk Teens (PI: Thompson; Mentor: Yen).
This qualitative study is exploring co-occurring psychosis-spectrum experiences and suicidal thoughts and behaviors among psychiatrically hospitalized teens at clinical high risk (CHR) for psychosis, with the goal of developing safety planning guidelines specifically tailored to CHR youth.