Beura Lab

Our laboratory seeks to understand how T cells integrate diverse local microbial and environmental stimuli at mucosal sites to shape distinct, dynamic, immune processes in health and disease. T cells are a key component of host defense against pathogenic infection in barrier mucosal surfaces, which are common sites of microbial entry. Often these potent, anti-pathogenic inflammatory responses need to be tightly regulated to maintain barrier integrity and vital physiologic functions. The mucosal immune system in the female reproductive tract (FRT) has evolved to mount a robust anti-pathogen defense while maintaining tolerance towards an immunologically foreign fetus. Thus, the FRT provides a unique model system to study T cell adaptation to diverse environmental inputs. Our research program is aimed to develop a more complete understanding of the fundamental biology of T cells in the reproductive mucosae. Furthermore, we seek to apply this knowledge to informing improved vaccination strategies, develop novel therapies against infection and malignancy and to advance maternal-fetal health.

Rotation students

We are now accepting rotation students. Interested applicants affiliated with the Pathobiology graduate program and MCB graduate program should directly contact Lalit at Lalit_Beura@brown.edu.

Post-doctoral Associates

The Beura Lab is recruiting a Postdoc interested in working in epithelial-immune interactions in the reproductive mucosa. Details of the application process can be found at http://apply.interfolio.com/145385. Interested candidates can also directly email Lalit at Lalit_Beura@brown.edu.