Selected Publications

Epithelial organoid supports resident memory CD8 T cell differentiation

Ulibarri MR*, Ying L*, Ramprashad JC, Han G, Hasan M, Mithila

F, Ma C, Gopinath S, Zhang N, Milner JJ, Beura LK.

bioRxiv (preprint). 2023 December | PMID: 38076957

Cellular interactions in resident memory T cell establishment and function

Mohammad H. Hasan, Lalit K Beura

Current Opinion in Immunology, February 2022 | PMID: 34794039

Developmental plasticity allows outside-in immune responses by resident memory T cells

Fonseca RF*, Beura LK*, Quarnstrom CQ*, Ghoneim H, Fan Y, Zebley CC, Scott MC, Fares-Frederickson NJ, Wijeyesinghe S, Thompson EA, Borges da Silva H, Vezys V, Youngblood B, Masopust D.

Nature Immunol. 2020 April | PMID: 32066954

The Functional Requirement for CD69 in Establishment of Resident Memory CD8+ T Cells Varies with Tissue Location.

Walsh DA, Borges da Silva H, Beura LK, Peng C, Hamilton SE, Masopust D, Jameson SC.

J Immunol. 2019 Aug 15 | PMID: 31243092

CD4+ resident memory T cells dominate immunosurveillance and orchestrate local recall responses.

Beura LK, Fares-Frederickson NJ, Steinert EM, Scott MC, Thompson EA, Fraser KA, Schenkel JM, Vezys V, Masopust D.

J Exp Med. 2019 May 6 | PMID: 30923043

Interstitial Migration of CD8αβ T Cells in the Small Intestine Is Dynamic and Is Dictated by Environmental Cues.

Thompson EA, Mitchell JS, Beura LK, Torres DJ, Mrass P, Pierson MJ, Cannon JL, Masopust D, Fife BT, Vezys V.

Cell Rep. 2019 Mar 12 | PMID: 30865878

US Immigration Westernizes the Human Gut Microbiome.

Vangay P, Johnson AJ, Ward TL, Al-Ghalith GA, Shields-Cutler RR, Hillmann BM, Lucas SK, Beura LK, Thompson EA, Till LM, Batres R, Paw B, Pergament SL, Saenyakul P, Xiong M, Kim AD, Kim G, Masopust D, Martens EC, Angkurawaranon C, McGready R, Kashyap PC, Culhane-Pera KA, Knights D.

Cell. 2018 Nov 1 | PMID: 30388453

The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells.

Borges da Silva H, Beura LK, Wang H, Hanse EA, Gore R, Scott MC, Walsh DA, Block KE, Fonseca R, Yan Y, Hippen KL, Blazar BR, Masopust D, Kelekar A, Vulchanova L, Hogquist KA, Jameson SC.

Nature. 2018 Jul | PMID: 29973721

T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells.

Beura LK, Wijeyesinghe S, Thompson EA, Macchietto MG, Rosato PC, Pierson MJ, Schenkel JM, Mitchell JS, Vezys V, Fife BT, Shen S, Masopust D.

Immunity. 2018 Feb 20 | PMID: 29466758

Intravital mucosal imaging of CD8+ resident memory T cells shows tissue-autonomous recall responses that amplify secondary memory.

Beura LK, Mitchell JS, Thompson EA, Schenkel JM, Mohammed J, Wijeyesinghe S, Fonseca R, Burbach BJ, Hickman HD, Vezys V, Fife BT, Masopust D.

Nat Immunol. 2018 Feb | PMID: 29311694

Tissue resident memory T cells and viral immunity.

Rosato PC, Beura LK, Masopust D.

Curr Opin Virol. 2017 Feb | PMID: 27987416

Normalizing the environment recapitulates adult human immune traits in laboratory mice.

Beura LK, Hamilton SE, Bi K, Schenkel JM, Odumade OA, Casey KA, Thompson EA, Fraser KA, Rosato PC, Filali-Mouhim A, Sekaly RP, Jenkins MK, Vezys V, Haining WN, Jameson SC, Masopust D.

Nature. 2016 Apr 28 | PMID: 27096360

Shortened Intervals during Heterologous Boosting Preserve Memory CD8 T Cell Function but Compromise Longevity.

Thompson EA, Beura LK, Nelson CE, Anderson KG, Vezys V.

J Immunol. 2016 Apr 1 | PMID: 26903479

Stromal cells control the epithelial residence of DCs and memory T cells by regulated activation of TGF-β.

Mohammed J, Beura LK, Bobr A, Astry B, Chicoine B, Kashem SW, Welty NE, Igyártó BZ, Wijeyesinghe S, Thompson EA, Matte C, Bartholin L, Kaplan A, Sheppard D, Bridges AG, Shlomchik WD, Masopust D, Kaplan DH.

Nat Immunol. 2016 Apr | PMID: 26901152

Quantifying Memory CD8 T Cells Reveals Regionalization of Immunosurveillance.

Steinert EM, Schenkel JM, Fraser KA, Beura LK, Manlove LS, Igyártó BZ, Southern PJ, Masopust D.

Cell. 2015 May 7 | PMID: 25957682

Lymphocytic choriomeningitis virus persistence promotes effector-like memory differentiation and enhances mucosal T cell distribution.

Beura LK, Anderson KG, Schenkel JM, Locquiao JJ, Fraser KA, Vezys V, Pepper M, Masopust D.

J Leukoc Biol. 2015 Feb | PMID: 25395301

T cell memory. Resident memory CD8 T cells trigger protective innate and adaptive immune responses.

Schenkel JM, Fraser KA, Beura LK, Pauken KE, Vezys V, Masopust D.

Science. 2014 Oct 3 | PMID: 25170049

SnapShot: resident memory T cells.

Beura LK, Masopust D.