Pressure-Enabled Regional Immuno-Oncology
PERIO-02
Clinical site for PERIO-02 study of intra-arterial administration of toll-like receptor agonist SD-101 in combination with systemic immune checkpoint blockade for hepatocellular carcinoma and intrahepatic cholangiocarcinoma sponsored by TriSalus Life Sciences (ClinicalTrials.gov NCT05220722)
Project Status: Active, Recruiting

PERIO-03
Clinical site for PERIO-03 study of retrograde transvenous administration of toll-like receptor agonist SD-101 in combination with systemic immune checkpoint blockade for locally-advanced pancreatic adenocarcinoma sponsored by TriSalus Life Sciences (ClinicalTrials.gov NCT05220722)
Project Status: Pending activation

Absorbable Inferior Vena Cava Filter
Clinical site for randomized trial of an absorbable inferior cava filter used for prevention of pulmonary embolism sponsored by Adient Medical  (ClinicalTrials.gov NCT05127915)
Project Status: Pending activation

Pulmonary Embolism – Thrombus Removal with Catheter-Directed Therapy (PE-TRACT)
Clinical site for randomized trial of anticoagulation with or without catheter-based therapies for treatment of submassive pulmonary embolism
(ClinicalTrials.gov NCT05591118)
Project Status: Active, Recruiting

Locoregional Therapies and Systemic Effector T-cell Repertoire
Investigating the changes of circulating peripheral blood T-cell populations after locoregional image-guided therapies as a potential biomarker for treatment outcomes
Project Status: Active, Recruiting

“Visualizing Recovery” in Interventional Oncology with Wearable Activity Trackers
Developing of a normative dataset of patient recovery intervals following common IO procedures such as ablation, transarterial (chemo)embolization, and radioembolization
Project Status: Completed (DOI: 10.1016/j.jvir.2023.04.010)


Machine Learning in Interventional Oncology
Training machine learning algorithms to better predict outcomes following image-guided ablation for treatment of primary and metastatic lung tumors
Project Status: Active

Tumor pH and Locoregional Therapies
Exploring of the complex interactions between low pH, hypoxia, and immune function within the tumor microenvironment as a mechanism for optimizing transarterial locoregional cancer therapies
Project Status: Active

Semi-automated Ablation Zone Margin Assessment
3D Slicer-based registration algorithm for near-real-time estimation of treatment margins during CT-guided thermal ablation with particular emphasis on application to small renal masses (GitHub)
Project Status: Active

TIPS vs BARTO/BATO: Optimal Treatment for Gastric Variceal Disease
Comparative outcome analysis between TIPS and BARTO/BATO in the setting of gastric variceal bleeding
Project Status: Active