Why is this important?
Reduce Overdoses
The illicit drug supply has changed. Fentanyl and fentanyl analogs have largely replaced heroin, heightening risk for fatal overdose.
Standardize Dosing
Fentanyl’s dominance in the drug supply has changed the therapeutic dose of treatment. The updated optimal buprenorphine dosing is still unknown.
Improve Lives
This study explores the impact of a standard or high dose of buprenorphine maintenance on treatment outcomes in patients with a history of fentanyl use.
Sponsors + Partners
Principal Investigator(s): Francesca Beaudoin, MD, PhD & Rachel Wightman, MD
Contact: francesca_beaudoin@brown.edu; rachelwightman@brown.edu
Brown University IRB Protocol # 2022003300