401-863-1303 optimalbup@brown.edu

A Brown University

Research Study

The main goal of the study is to learn if a higher daily dose of buprenorphine compared to a standard dose of buprenorphine:

  • better controls symptoms
  • improves treatment engagement
  • reduces the risk of an overdose¬†

Who can participate?

What are the eligibility requirements?

 

  • English speaking
  • 18 years or older
  • Diagnosed with moderate to severe opioid use disorder (OUD)
  • Initiating or continuing ‚ȧ16mg buprenorphine for treatment of OUD
  • Have a history of fentanyl use
  • Reside in Rhode Island
  • Able to provide informed consent
What would exclude me?

 

  • Currently pregnant or breastfeeding
  • Currently a prisoner or in police custody

Why is this important?

N

Reduce Overdoses

The illicit drug supply has changed. Fentanyl and fentanyl analogs have largely replaced heroin heightening risk for fatal overdose

N

Standardize dosing

Fentanyl is changing the calculation of treatment and optimal buprenorphine dosing is unknown

N

Improve Lives

This study explores the impact of the dose of buprenorphine maintenance on treatment outcomes in patients with a history of fentanyl use