Creton Lab

Research in the Creton laboratory is focused on brain development and behavior, using zebrafish as a model system. The studies aim to provide a better understanding of cell signaling in the brain and contribute to the prevention and treatment of various human disorders, including visual impairment, developmental brain disorders, and Alzheimer’s disease.

 

Robbert Creton
Robbert Creton
Sayali Gore
Sayali Gore
Picture of Thais
Thais Del Rosario Hernandez

 

 

 

 

 

Allison Lowe
Allison Lowe
Lawrence Heller
Lawrence Heller
Mallika Chatterjee
Mallika Chatterjee

 

 

 

 

 

 

 

Lab members

 

Rohit Kakodkar
Rohit Kakodkar
Jill Kreiling
Jill Kreiling
Ruth Colwill
Ruth Colwill

 

 

 

 

 

 

 

Collaborators

  • Rohit Kakodkar Ph.D., Research Software Engineer, Center for Computation and Visualization
  • Jill Kreiling Ph.D., Associate Professor of Molecular Biology, Cell Biology and Biochemistry
  • Ruth M. Colwill Ph.D., Professor of Cognitive, Linguistic and Psychological Sciences
  • Narendra Joshi, Graduate Student
  • Molly Rajsombath, Research Assistant

 

Lab Alumni

  • Rahma Ibrahim
  • Cameron Brown
  • Lily Zhou

Address

The Creton Laboratory
Department of Molecular Biology, Cell Biology and Biochemistry
Brown University
Bio-Medical Center (BMC) 187
185 Meeting Street
Providence, RI 02912

Phone (Lab): 401-863-6512

 

On the Web

Publications: https://www.ncbi.nlm.nih.gov/myncbi/robbert.creton.1/bibliography/public/
Faculty profile: https://vivo.brown.edu/display/rcretonp

Projects in the Creton Lab:  https://sites.brown.edu/zebrafish/creton/projects

Github page: https://github.com/Creton-Lab
Protocols page: https://creton-lab.github.io/Creton-Lab/

Zebrafish calendar for embryo collection:  Calendar

 

NEWS

 

Lab Group Photo
MCBGP Retreat

 

 

September 1, 2023: MCB Graduate Program retreat. Congratulations Narendra!

 

 

 

 

8 cage imaging system
8-Cage Imaging System

 

 

 

May 19, 2023: Paper on an 8-cage imaging system for the automated analysis of mouse behavior
https://www.nature.com/articles/s41598-023-35322-1

 

 

 

 

 

Hierarchical cluster featuring 17 CsA-like compounds
Hierarchical Clustering

 

February 23, 2023: Publication on the development of a new tool to analyze zebrafish larvae behavior
https://www.nature.com/articles/s41598-023-30303-w

 

 

 

 

96-well plate
Screen of FDA-approved drugs

 

April 21st, 2022:  Publication on CsA-type drugs for the prevention and treatment of Alzheimer’s disease.  https://www.nature.com/articles/s41598-022-10133-y

 

 

 

 

Picture of Rahma
Rahma’s poster

 

April 7th, 2022: Rahma at the Annual Biological Sciences Senior Research and Capstone Poster Day.  Congratulations Rahma!

 

 

 

 

 

 

 

 

Snow at Brown
January 2022 – Snow at Brown

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

zebrafish larvae and cluster
Behavioral profiles

 

August 2021: Paper on zebrafish as a model for calcineurin-dependent brain function.  https://pubmed.ncbi.nlm.nih.gov/34425181/

 

 

Signaling pathway
Calcineurin signaling

 

September 2020: New NIH R01 Award on ‘Emerging imaging technologies for automated analyses of calcineurin-dependent brain function‘.

 

 

 

 

 

 

microplate
High-throughput imaging of behavior

 

September 2019: Paper on the analysis of vertebrate vision in a 384-well imaging system
https://www.nature.com/articles/s41598-019-50372-0

 

 

 

 

ZDM12 Poster
Sara’s ZDM12 poster

 

July 2019: Sara Tucker Edmister presented a poster at ZDM12, the 12th meeting of the Zebrafish Disease Models Society, Boston, MA.

 

 

 

 

12-well plate
Research Feature

 

January 2018: Article in Research Features
https://researchfeatures.com/small-but-perfectly-formed-zebrafish-model-the-human-brain/