PUBLICATIONS

Full List of Publications at NCBI

  2019

Thomson GJ, Hernon C, Austriaco N, Shapiro RS, Belenky P, Bennett RJMetabolism-induced oxidative stress and DNA damage selectively trigger genome instability in polyploid fungal cells. EMBO J.  38(19):e101597.

 

Anderson MZ, Thomson GJ, Hirakawa MP, Bennett RJ.  A ‘parameiosis’ drives depolyploidization and homologous recombination in Candida albicans.  Nat Comm10(1):4388. 

Liang SH, Anderson MZ, Hirakawa MP, Wang JM, Frazer C, Alaalm LM, Thomson GJ, Ene IV, Bennett RJ Hemizygosity enables a mutational transition governing fungal virulence and commensalism.  Cell Host and Microbe. 25(3):418-431. 

Mancera E, Frazer C, Porman AM, Ruiz-Castro S, Johnson AD, Bennett RJ.  Genetic modification of closely related Candida species.  Front Microbiol. 2019 10:357

 

Ene IV, Bennett RJ, Anderson MZ.  Mechanisms of genome evolution in Candida albicans.  Curr Opin Microbiol. 2019 52:47-54. 

 

Frazer C, Hernday AD, Bennett RJ.  Monitoring phenotypic switching in Candida albicans and the use of next-gen fluorescence reporters. Curr Protoc Microbiol. 2019 e76. 

  2018

Beekman C, Jiang Z, Suzuki BM, Palmer JM, Lindner DL, O’Donoghue AJ, Knudsen GM, Bennett RJ.  Characterization of PdCP1, a serine carboxypeptidase from Pseudogymnoascus destructans, the causal agent of White-nose Syndrome.  Biol Chem. 2018 399(12):1375-1388. 

Beekman CN, Meckler L, Kim E, Bennett RJ.  Galleria mellonella as an insect model for P. destructans, the cause of White-nose Syndrome in bats.  PLoS One. 2018 13(9):e0201915.

Ene IV, Farrer RA, Hirakawa MP, Agwamba K, Cuomo CA, Bennett RJ.  Global analysis of mutations driving microevolution of a heterozygous diploid fungal pathogen.  Proc Natl Acad Sci USA. 2018 115(37):E8688-E8697. 

Rosenberg A, Ene IV, Bibi M, Zakin S, Segal ES, Ziv N, Dahan AM, Colombo AL, Bennett RJ, Berman J.  Antifungal tolerance is a subpopulation effect distinct from resistance and is associated with persistent candidemia.  Nat Commun. 2018 9(1):2470.

Du H, Zheng Q, Bing J, Bennett RJ, Huang G.  A coupled process of same- and opposite-sex mating generates polyploidy and genetic diversity in Candida tropicalis.  PLoS Genet. 2018 14(5):e1007377. 

  2017

Scaduto CM, Kabrawala S, Thomson GJ, Scheving W, Ly A, Anderson MZ, Whiteway M, Bennett RJ. Epigenetic control of pheromone MAPK signaling determines sexual fecundity in Candida albicans.  Proc Natl Acad Sci USA. 2017 114(52):13780-13785. 

Hirakawa MP, Chyou DE, Huang D, Slan AR, Bennett RJ.  Parasex generates phenotypic diversity de novo and impacts drug resistance and virulence in Candida albicans.  Genetics. 2017 207(3):1195-1211. 

Regan H, Scaduto CM, Hirakawa MP, Gunsalus K, Correia-Mesquita TO, Sun Y, Chen Y, Kumamoto CA, Bennett RJ, Whiteway M.  Negative regulation of filamentous growth in Candida albicans by Dig1p.  Mol Microbiol. 2017 105(5):810-824. 

Anderson MZ, Saha A, Haseeb A, Bennett RJ.  A chromosome 4 trisomy contributes to increased fluconazole resistance in a clinical isolate of Candida albicans.  Microbiology. 2017 163(6):856-865.

  2016

Anderson MZ, Porman AM, Wang N, Mancera E, Huang D, Cuomo CA, Bennett RJ A multistate toggle switch defines fungal cell fates and is regulated by synergistic genetic cues.  PLoS Genet. 2016 12(10):e1006353.

Mallick EM, Bergeron AC, Jones SK Jr, Newman ZR, Brothers KM, Creton R, Wheeler RT, Bennett RJ.  Phenotypic plasticity regulates Candida albicans interactions and virulence in the vertebrate host.  Front Microbiol. 2016 7:780.

Bennett RJ, Turgeon BG.  Fungal Sex: The Ascomycota.  Microbiol Spectr. 2016 4(5).  

Lohse MB, Ene IV, Craik VB, Hernday AD, Mancera E, Morschhäuser J, Bennett RJ, Johnson AD.  Systematic genetic screen for transcriptional regulators of the Candida albicans white-opaque switch.  Genetics. 2016 203(4):1679-92. 

Sun Y, Gadoury C, Hirakawa MP, Bennett RJ, Harcus D, Marcil A, Whiteway M.  Deletion of a Yci1 domain protein of Candida albicans allows homothallic mating in MTL heterozygous cells.  MBio. 2016 7(2):e00465-16. 

  2015

Jones SK Jr, Clarke SC, Craik CS, Bennett RJ.  Evolutionary selection on barrier activity: Bar1 Is an aspartyl protease with novel substrate specificity.  MBio. 2015 6(6):e01604-15. 

Bennett RJThe parasexual lifestyle of Candida albicans.  Curr Opin Microbiol. 2015 28:10-7.  

Frazer C, Joshi M, Delorme C, Davis D, Bennett RJ, Allingham JS.  Candida albicans kinesin Kar3 depends on a Cik1-Like regulatory partner protein for its roles in mating, cell morphogenesis, and bipolar spindle formation.  Eukaryot Cell. 2015 14(8):755-74. 

 O’Donoghue AJ, Knudsen GM, Beekman C, Perry JA, Johnson AD, DeRisi JL, Craik CS, Bennett RJ.  Destructin-1 is a collagen-degrading endopeptidase secreted by Pseudogymnoascus destructans, the causative agent of white-nose syndrome.  Proc Natl Acad Sci USA. 2015 112(24):7478-83. 

Mancera E, Porman AM, Cuomo CA, Bennett RJ, Johnson AD. Finding a missing gene: EFG1 regulates morphogenesis in Candida tropicalis.  G3 (Bethesda). 2015 5(5):849-56.

Hirakawa MP, Martinez DA, Sakthikumar S, Anderson MZ, Berlin A, Gujja S, Zeng Q, Zisson E, Wang JM, Greenberg JM, Berman J, Bennett RJ*, Cuomo CA*.  Genetic and phenotypic intra-species variation in Candida albicans.  Genome Res. 2015 25(3):413-25. 

 

  2014

Bennett RJ, Forche A, Berman J. Rapid mechanisms for generating genome diversity: whole ploidy shifts, aneuploidy, and loss of heterozygosity.  Cold Spring Harb Perspect Med. 2014 4(10). pii: a019604. 

Ene IV, Bennett RJ.  The cryptic sexual strategies of human fungal pathogens.  Nat Rev Microbiol. 2014 12(4):239-51.

 Jones SK Jr, Hirakawa MP, Bennett RJ.  Sexual biofilm formation in Candida tropicalis opaque cells.  Mol Microbiol. 2014 92(2):383-98. 

Sherwood RK, Scaduto CM, Torres SE, Bennett RJ.  Convergent evolution of a fused sexual cycle promotes the haploid lifestyle.  Nature. 2014 506(7488):387-390.

  2013

Mallick EM, Bennett RJ.  Sensing of the microbial neighborhood by Candida albicans. PLoS Pathog. 2013 9(10):e1003661. .

Seervai RN, Jones SK Jr, Hirakawa MP, Porman AM, Bennett RJ.  Parasexuality and ploidy change in Candida tropicalis.  Eukaryot Cell. 2013 12(12):1629-40. 

Lin CH, Kabrawala S, Fox EP, Nobile CJ, Johnson AD, Bennett RJ.  Genetic control of conventional and pheromone-stimulated biofilm formation in Candida albicans.  PLoS Pathog. 2013;9(4):e1003305.

Porman AM, Hirakawa MP, Jones SK, Wang N, Bennett RJ.  MTL-independent phenotypic switching in Candida tropicalis and a dual role for Wor1 in regulating switching and filamentation. PLoS Genet. 2013 9(3):e1003369.

Si H, Hernday AD, Hirakawa MP, Johnson AD, Bennett RJ. Candida albicans white and opaque cells undergo distinct programs of filamentous growth. PLoS Pathog. 2013 9(3): e1003210. 

Shintaku T, Glass KA, Hirakawa MP, Longley SJ, Bennett RJ, Bliss JM, Shaw SK.  Human endothelial cells internalize Candida parapsilosis via N-WASP-mediEmerging and emerged pathogenic Candida species: beyond the Candida albicans paradigm.ated endocytosis. Infect Immun. 2013 81(8):2777-87. 

Papon N, Courdavault V, Clastre M, Bennett RJ.  Emerging and emerged pathogenic Candida species: beyond the Candida albicans paradigm.  PLoS Pathog. 2013 9(9):e1003550.

  2011

Porman AM, Alby K, Hirakawa MP, Bennett RJ.  Discovery of a phenotypic switch regulating sexual mating in the opportunistic fungal pathogen Candida tropicalis. Proc Natl Acad Sci USA. 2011 108(52):21158-63.. 

Lin CH, Choi A, Bennett RJ.  Defining pheromone-receptor signaling in Candida albicans and related asexual Candida species.  Mol Biol Cell. 2011 22(24):4918-30. 

Jones SK Jr, Bennett RJ.  Fungal mating pheromones: choreographing the dating game.  Fungal Genet Biol. 2011 48(7):668-76. 

  2010

Bennett RJ.  Coming of age–sexual reproduction in Candida species.  PLoS Pathog. 2010 6(12):e1001155. 

Alby K, Schaefer D, Sherwood RK, Jones SK Jr, Bennett RJ.  Identification of a cell death pathway in Candida albicans during the response to pheromone.  Eukaryot Cell. 2010 9(11):1690-701.  

  2009

Sherwood RK, Bennett RJFungal meiosis and parasexual reproduction–lessons from pathogenic yeast.  Curr Opin Microbiol. 2009 12(6):599-607. 

Alby K, Schaefer D, Bennett RJ.  Homothallic and heterothallic mating in the opportunistic pathogen Candida albicans.  Nature. 2009 460(7257):890-3. 

Bennett RJA Candida-based view of fungal sex and pathogenesis..  Genome Biol. 2009;10(7):230. 

Alby K, Bennett RJ.  Stress-induced phenotypic switching in Candida albicans.  Mol Biol Cell. 2009 20(14):3178-91.

  2008

Forche A, Alby K, Schaefer D, Johnson AD, Berman J, Bennett RJ.The parasexual cycle in Candida albicans provides an alternative pathway to meiosis for the formation of recombinant strains.  PLoS Biol. 2008 6(5):e110. 

  2007

Schaefer D, Côte P, Whiteway M, Bennett RJ.  Barrier activity in Candida albicans mediates pheromone degradation and promotes mating.  Eukaryot Cell. 2007 6(6):907-18.