The Darling Lab and Draper article “Microparticles with tunable, cell-like properties for quantitative acoustic mechanophenotyping” was accepted for publication in Microsystems and Nanoengineering. This study further developed our lab’s cell-like polymer microparticles to vary not only in size and stiffness… Continue Reading
The Darling Lab article “Chondrogenesis of Adipose-Derived Stem Cells Using an Arrayed Spheroid Format” was accepted for publication in Cellular and Molecular Bioengineering. This study demonstrated that mesenchymal stem cells cultured as 3D spheroids in a highly arrayed format could undergo… Continue Reading
The Darling Lab article “Discovery of surface biomarkers for cell mechanophenotype via an intracellular protein-based enrichment strategy” was accepted for publication in Cellular and Molecular Life Sciences. This study described how to identify surface markers for as yet un-sortable cell types.… Continue Reading
The Darling Lab article “Temporal responsiveness of adipose-derived stem/stromal cell immuneplasticity” was accepted for publication in Experimental Cell Research. This study described the response of stem cells to inflammatory stimuli over time. It also revealed that macrophages can be modulated to an… Continue Reading
The Darling Lab article “Quantification of Antibody Persistence for Cell Surface Protein Labeling” was accepted for publication in Cellular and Molecular Bioengineering. This study demonstrated a broadly accessible protocol for evaluating the persistence of antibody binding on cell surfaces, which is… Continue Reading
The Darling Lab article “Single‐Cell Microgels for Diagnostics and Therapeutics” was accepted for publication in Advanced Functional Materials. This progress report gathers and synthesizes the newest findings related to single-cell encapsulation as a resource for both new and experienced scientists in… Continue Reading
The Darling Lab article “Force sensors for measuring microenvironmental forces during mesenchymal condensation” was accepted for publication in Biomaterials. This study demonstrated an exciting, new way to directly measure the microscale forces that cells exert, and have exerted on them, in… Continue Reading
The Darling Lab article “Effect of elastic modulus on inertial displacement of cell-like particles in microchannels” was accepted for publication in Biomicrofluidics. This study demonstrated how polymer cell mimics of defined size and stiffness could be used to map out the… Continue Reading
The Darling Lab article “Mass-Added Density Modulation for Sorting Cells Based on Differential Surface Protein Levels” was accepted for publication in Cytometry Part A. This study demonstrated a new methodology for non-binary separation of cells by surface protein expression that makes… Continue Reading
The Darling Lab article “Generating cell type-specific protein signatures from non-symptomatic and diseased tissues” was accepted for publication in Annals of Biomedical Engineering. This study demonstrated how diverse cell subpopulations can be enriched for using highly specific, intracellular targets and subsequently… Continue Reading