The Darling Lab article “Identifying immunomodulatory subpopulations of adipose stromal vascular fraction and stem/stromal cells through single-cell transcriptomics and bulk proteomics” (SharedIt link) was accepted for publication in Stem Cell Reviews and Reports. This study used a combination of proteomic… Continue Reading
The Darling Lab article “Selection of Force Sensors for In Situ Measurement of Neotissue Microenvironments” was accepted for publication in Tissue Engineering, Part A. This study investigated how the size, elastic modulus, and surface coating of microscale sensors affects forces exerted on… Continue Reading
The conference paper “Physiologically relevant microparticles with mechanically tunable properties for acoustophoretic and microfluidic device calibration” from the Darling Lab and collaborators at Draper was recently published in Proceedings of Meetings on Acoustics. This study modified our existing cell mimic… Continue Reading
The Darling Lab and Draper article “Microparticles with tunable, cell-like properties for quantitative acoustic mechanophenotyping” was accepted for publication in Microsystems and Nanoengineering. This study further developed our lab’s cell-like polymer microparticles to vary not only in size and stiffness… Continue Reading
The Darling Lab article “Chondrogenesis of Adipose-Derived Stem Cells Using an Arrayed Spheroid Format” was accepted for publication in Cellular and Molecular Bioengineering. This study demonstrated that mesenchymal stem cells cultured as 3D spheroids in a highly arrayed format could undergo… Continue Reading
The Darling Lab article “Discovery of surface biomarkers for cell mechanophenotype via an intracellular protein-based enrichment strategy” was accepted for publication in Cellular and Molecular Life Sciences. This study described how to identify surface markers for as yet un-sortable cell types.… Continue Reading
The Darling Lab article “Temporal responsiveness of adipose-derived stem/stromal cell immuneplasticity” was accepted for publication in Experimental Cell Research. This study described the response of stem cells to inflammatory stimuli over time. It also revealed that macrophages can be modulated to an… Continue Reading
The Darling Lab article “Quantification of Antibody Persistence for Cell Surface Protein Labeling” was accepted for publication in Cellular and Molecular Bioengineering. This study demonstrated a broadly accessible protocol for evaluating the persistence of antibody binding on cell surfaces, which is… Continue Reading
The Darling Lab article “Single‐Cell Microgels for Diagnostics and Therapeutics” was accepted for publication in Advanced Functional Materials. This progress report gathers and synthesizes the newest findings related to single-cell encapsulation as a resource for both new and experienced scientists in… Continue Reading
The Darling Lab article “Force sensors for measuring microenvironmental forces during mesenchymal condensation” was accepted for publication in Biomaterials. This study demonstrated an exciting, new way to directly measure the microscale forces that cells exert, and have exerted on them, in… Continue Reading