A Proposed Ligand to Increase the Binding of SNO- in an Iron (II) Complex

cnguye18 CURE Projects, Spring 2021, , ,
CHEM 500L CURE Poster - Logan Chin
A brief infographic that conveys the project we worked on this semester, written in an approachable style.

Class: CHEM 0500 – Inorganic Chemistry Lab

Instructor(s): Dr. Eric Victor

Student(s): Logan Chin (Biochemistry and Molecular Biology, ’23), Matthew Shinkar, Noah Feng, Casey Chan

“This CURE has been special because of the unique accessibility, as this lab was done completely remotely, using computers and math in order to simulate chemistry.”

-Logan Chin

Description:

Our project investigated how we could enhance the binding of a ligand, SNO-, through its sulfur to an iron ion through other ligands bound to the ion. We used Brown’s supercomputer cluster, OSCAR, to do computational chemistry to see how various ligands affected the SNO- binding, and then we took all the best parts of each ligand that we “made” and combined them into one.

This CURE has been special because of the unique accessibility, as when one thinks about a chemistry lab, it’s usually wet lab chemistry where the contents of various beakers are mixed together- however, this lab was done completely remotely, using computers and math in order to simulate chemistry.